Today is #MSWL day over on Twitter. If you have an account, be sure to pop over there and see who wants what in terms of manuscripts.
Susan recently blogged about what she would like to find this past year. She is interested in:
Picture books that click in terms of the childhood experience (Alexander and the Terrible, Horrible, No Good, Very Bad Day), concept books (Not a Box), great character stories like Olivia or Pigeon, and lyrical, informational books (Over and Under the Snow).
Middle grade mysteries ala US Agatha Christie, edgy and dark stories that push boundaries, contemporary stories with STEM interested female characters, historical fiction, and fantasy.
Young adult stories that focus on family, siblings and strong parent/child relationships, rich world building, non-Euro American historical fantasy, science fiction that deals with changes that might happen in our lifetimes, epistolary novels, unreliable narrators and more.
Good luck on your agent searches! I still have two pitches out and am getting ready to work on a third.